by Annie De Groot | Nov 26, 2013 | Thinking Out Loud -Blog
Tired of the same old Turkey? Even fully human antibodies can be immunogenic (see Mike Clark’s nice paper about that at the link below). It’s about time that someone came up with a new idea. So, we did. . . . tolerization is the process of introducing...
by Annie De Groot | Nov 26, 2013 | News
Beyond humanization and de-immunization: tolerization as a method for reducing the immunogenicity of biologics Expert Rev. Clin. Pharmacol. 6(6), 651–662 (2013) Abstract Immune responses to some monoclonal antibodies (mAbs) and biologic proteins interfere with their...