EpiVax Posters

Below are a number of selected EpiVax Posters:

Protein Therapeutics / Deimmunization / Tolerization (Using Tregitopes)

• The Two-Faced Cancer Neo-Epitope: Innovative Immunoinformatic Approaches for Mutanome-Directed Cancer Immunotherapry – June 2017
• Ancer: An Innovative Cancer Neoantigen Prediction System – March 2017
• Predicting Immunogenicity in the Era of Personalized Medicine: A Need for Individual Risk Assessment – May 2016
• The ISPRI Toolkit Rapidly Screens Biologic Product Candidates for Immunogenic Potential Driven by T cell Epitope Content and Foreignness – May 2016
• Regulating Immune Responses to Biologics: Validation of Screening, Deimmunization and Tolerization Approaches – May 2014
• Tolerization as a Rational Design Approach for Reducing the Immunogenicity of Biologics (Campath) – May 2014
• T-Cell Dependent Immunogenicity of Protein Therapeutics: Preclinical Assessment and Mitigation – May 2014
• In-silico prediction of HLA-DP and -DQ epitope content is poorly correlated with clinical immunogenicity of therapeutic proteins – May 2013
• Immunogenicity Analysis of Chinese Hamster Ovary (CHO) Host Cell Protein Contaminants in Therapeutic Protein Formulations – May 2013
• Immunogenic Biologics: Validation of Screening, Deimmunization and Tolerization Approaches – April 2013
• In silico High Throughput Pre-clinical Determination of Monoclonal Antibody Immunogenicity – April 2013

Tregitope

• Albumin Delivery of Tregitope Peptides for Tolerance Induction in Autoimmunity and Inflammatory Disease – May 2014
• Tregitope Applications to Tolerance Induction in Autoimmune Disease and Therapeutic Protein Immunogenicity – May 2014
• Antigen-specific tolerance induction by Tregitopes in vivo. – April 2013
• Tregitopes: The active ingredient in IVIG-mediated tolerance induction? – April 2013

Vaccine

• High-Value T Cell Epitope Selection for Mutanome-Directed Cancer Immunotherapy Using an Innovative Cancer Neo-Epitope Classification System  – September 2016
• Improved Personalized Vaccine and Adoptive Cell Transfer Immunotherapy Design by Immunoinformatic Analysis of Cancer Neo-epitopes – March 2016
• Side-stepping Regulatory T Cell-Mediated Evasion
  in Chronic Viral Infection to Build Better Vaccines – April 2015
• Immunogenicity of Teffector and Treg epitopes from H7N9 avian-origin influenza: Impact of cross-reactivity with the human genome
• Highly Immunogenic Vaccine For Prevention and Therapy of Malignant Mesothelioma – April 2013
• The Two-faced T cell Epitope: Examining the Host-Microbe Interface with JanusMatrix – April 2013
• FastVax: Making vaccines “on demand” A potential solution for emerging pathogens and biodefense? – October 2013
• Cross-reactive influenza H1N1 T cell epitopes identified by immunoinformatic methods stimulate CD4+ T cell responses – October 2013
• iVAX: A Sophisticated Suite of Online Vaccine Design Tools #2 – October 2013